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KBP-7018 hydrochloride
CAS No. 1613437-67-4
KBP-7018 hydrochloride( KBP 7018 hydrochloride | KBP7018 hydrochloride )
Catalog No. M12342 CAS No. 1613437-67-4
A novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 963 | Get Quote |
|
| 50MG | 1962 | Get Quote |
|
| 100MG | 2520 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameKBP-7018 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionA novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively.
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DescriptionA novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively; also potently inhibits FLT3, VEGFR2, Fyn, PDGFRα and VEGFR2; shows promising outcomes for the treatments of idiopathic pulmonary fibrosis (IPF).
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In Vitro——
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In Vivo——
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SynonymsKBP 7018 hydrochloride | KBP7018 hydrochloride
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PathwayAngiogenesis
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Targetc-Kit
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Recptorc-Kit
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Research Area——
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Indication——
Chemical Information
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CAS Number1613437-67-4
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Formula Weight575.06
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Molecular FormulaC31H31ClN4O5
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Purity>98% (HPLC)
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Solubility——
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SMILESCOC(=O)C1=CC2=C(C=C1)C(=C(N2)O)C(=NC3=CC4=C(C=C3)N(CC4)C(=O)CN5CCOCC5)C6=CC=CC=C6.Cl
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Chemical NameMethyl (Z)-3-(((1-(2-morpholinoacetyl)indolin-5-yl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Huang Z, et al. ACS Med Chem Lett. 2017 Sep 30;8(11):1142-1147.
2. Huang Z, et al. Drug Des Devel Ther. 2015 Aug 5;9:4319-28.
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